How effective is Avastin as targetted therapy for the metastatic colorectal cancer?
Taking Avastin, an FDA-approved monoclonal antibody and anti-angiogenesis drug (almost always in combination with intravenous 5-FU), for metastatic colorectal cancer is NOT exactly like the old Doc?s advice: ?Take two Aspirins and call me in the morning!?
This is a serious medical issue/decision that must be thoroughly discussed with the patient?s attending physician/oncologist and other members of the interdisciplinary treatment team.
As with any chemotherapy regime the side effects could vary from patient to patient; BUT they are potentially VERY SERIOUS (e.g. gastrointestinal perforation, hemoptysis, severe wound healing complications, etc.) ? One of my most precious friends is currently on it, and I can tell you, it has NOT exactly been a walk in the park for him! 
You may find the following web sites quite informative (if you haven?t seen them already, that is):
http://www.avastin.com/avastin/index.jsp?hl=en&q=Avastin
http://www.gene.com/gene/products/information/oncology/avastin/
http://www.drugs.com/avastin.html
Be well always, and all the best to your ?loved one?.
.
simonw
My friend took Avastin on a trial and did well. She had to drop out because of a pulmonary embolism.
That?s rare but make sure your mother is closely supervised for her own security.
from your own site.
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